98858vip威尼斯(China)集团有限公司·官方网站

The data-driven genotype construction platform based on high-throughput flow imaging has the characteristics of high throughput, automation, and high sensitivity. By using CRISPR high-throughput genotype construction, droplet microfluidics, and ultra-high-throughput characterization testing technology, the relationship between phenotypic genes, metabolism and correlation of production strains was deeply explored from the whole genome, such as analyzing the phenotype, genes, metabolism, etc. of HMOs production strains, and then screening out strains with better expression performance and more stable strains to achieve the construction of efficient strains.

The combination of bioinformatics and A!technology plays a synergistic role in enzyme research and proteomics research, providing us with powerful tools and methods for in-depth understanding of the function and properties of enzymes and the simulation of protein spatial structure. The breakthrough of generative AI technology has fully released the value of biological big data, and the complete data closed loop built by "generation, feedback, and optimization" can break through the limits of human computing and bring biological computing into the AI era.

Through gene editing technology, the required functional DNA fragments are introduced into model engineered bacteria, such as Escherichia coli and Pichia pastoris, to change the genetic information of the strains at the genetic level, and regulate their production capacity and the diversity of target products.

It is composed of fermentation laboratory and testing laboratory, equipped with fermentation tanks of different volumes of 5L-50L-100L-1000L, and the fermentation process is scaled up from 0-1-10 to establish the basic conditions for industrial production. The testing laboratory is equipped with a variety of precision testing instruments and develops a variety of detection methods to complete the detection and separation of target product concentration, impurities and isomer components, and realize the optimization of strain metabolism path, high-density fermentation, high-purity separation and purification, product quality control and other purposes.